PROTECTion against Endocrine Disruptors; Detection, mixtures, health effects, risk assessment and communication.

Jobs

PROTECTED is a Marie Sklowdowska-Curie Innovative Training Network (MCSA-ITN) with the primary research aim to create an innovative expertise required to manage the human and environmental impacts of endocrine disruptors (EDs) and their mixtures in the food chain, and environment. In total, 15 Early Stage Researchers (ESRs) will be appointed by the PROTECTED consortium for 36 months each.


Description

PROTECTED aims to develop expertise and protective capabilities against Endocrine Disruptors (EDs). EDs and their mixtures are a modern day health concern leading to failing ecological systems, poor agricultural production and health effects such as obesity, cancer and infertility. While analytical methods have advanced enormously, focus has been mainly on synthetic chemicals, overlooking emerging EDs and real-life multiple substance exposure. A new generation of creative, entrepreneurial and innovative early-stage researchers equipped with skills to assess and understand the real-life risk of complex mixtures of EDs and trained to convert resulting knowledge and ideas into accessible tools and services for the long-term control of potential ED risk is urgently needed. The PROTECTED Innovative Training Network [ITN] proposes a holistic approach by providing 15 individual, personalised research projects with exposure to scientific, innovative and entrepreneurial training mobility across the ITN. The intersectorial network is comprised of 12 training sites at academia, research centres, a bioassay technology SME, a QSAR technology SME, water provider, and animal feed supplier. Together they cover multiple disciplines including analytical science of food, feed, and environment, epidemiology, risk assessment, social science and toxicology. This combined expertise enables a highly focused program for developing novel tools and concepts and training for the detection, analysis and improved risk assessment of EDs, especially mixture effects. Methodology will include emerging technologies; multiplexed analysis, mixture modelling, mechanistic and exposure studies, explants and cell or whole organism bioassays. The project will provide a unique and high level of training for a new generation of specialists with transferable skills and enhanced career perspectives. These specialists will ultimately aid the efficient development of future control strategies for improved health.

The project will be coordinated by Dr Lisa Connolly at Queen's University Belfast and involve both European and International collaborators. There are 15 ESR positions available throughout the project network and within the following research fields:


Research Fields:

  • Biological sciences > Other
  • Chemistry > Biochemistry
  • Chemistry > Computational chemistry
  • Communication sciences > Science communication
  • Computer science > Modelling tools
  • Environmental science > Other
  • Medical sciences > Other
  • Pharmacological sciences > Toxicology
  • Technology > Medical technology

MSCA-ITN eligibility criteria

There are strict eligibility requirements for the ESR PhD positions in MSCA-ITN. Please ensure that you qualify before applying, as ineligible candidates cannot be considered.

  • Applicants should not have resided or performed their main activity (work, studies, etc) in the country of the host institution for more than 12 months in the 3 year period immediately prior to the start date of the PhD research.
  • Applicants for the ESR PhD positions should be in the first 4 years (full-time equivalent) of their research careers and not yet have been awarded a doctorate. This 4 year period is measured from the date of obtaining the degree which would formally entitle to embark on a doctorate.

Benefits


ESR Positions and application details

Closing date: Monday 9 January 2017.

Anticipated interview date: Friday 27 January 2017.


Queen’s University Belfast, United Kingdom

ESR1 will focus on exploring consumer perceptions and understanding of EDs in in the environment and food chain for the development of efficient risk communication strategies. This project will involve the use of qualitative focus group and survey methods for validation.

For further information contact: Mrs Joyce Watterson (joyce.watterson@qub.ac.uk)

APPLY ONLINE via the QUB application portal (Ref: 16/105007).





University of Liege, Belgium

ESR5 will focus on zebrafish larvae tests for the study of ED mixture effects on early development and behaviour and gene regulation events, especially in the brain. Candidate genes for ED biomarkers may be identified, providing important ecotoxicological information concerning effects on the vertebrate aquatic fauna. This project will involve the use of in vivo zebrafish larvae tests and molecular biology techniques.

For further information contact: Dr Marc Muller (m.muller@ulg.ac.be)

APPLY

by sending a CV and letter of motivation to Dr Marc Muller (m.muller@ulg.ac.be)


National Institute for Agricultural Research (INRA), Toulouse, France

ESR6 will focus on exploring the effects of the mycotoxin Zearalenone and co-occurring mycotoxin mixtures on the function of the intestine. This project will involve the use of tissue culture techniques and high throughput assays such as transcriptomics.

For further information contact: Dr Isabelle Oswald (Isabelle.Oswald@toulouse.inra.fr)

APPLY

by sending a CV and letter of motivation to Dr Isabelle Oswald (Isabelle.Oswald@toulouse.inra.fr)



Norwegian University of Life Sciences, Oslo, Norway

ESR8 will use Zebrafish models in studies of exposure effects of ED and realistic mixtures thereof. Behavioural outcomes, combined with morphology and transcriptomics studies will be used to investigate exposure effects on neurodevelopment, immune function and their interactions. In addition, transgenerational studies and population modelling will be carried out to investigate population level effects.

For further information contact: Prof Erik Ropstad (erik.ropstad@nmbu.no)

APPLY ONLINE via the NMBU Website (Ref: 16/05879).







BioDetection Systems, Amsterdam, The Netherlands

ESR14 will focus on the development of a combined chemical-biological detection system for ED mixtures affecting human development. This project will involve the use of analytical detection systems, cell culture techniques and in vitro bioassay development.

For further information contact: Dr Bart Van der Burg (Bart.van.der.Burg@bds.nl)

APPLY

by sending a CV and letter of motivation to Dr Bart Van der Burg (Bart.van.der.Burg@bds.nl)


BioDetection Systems, Amsterdam, The Netherlands

ESR15 will focus on the development of a combined chemical-biological detection system for ED mixtures affecting animal reproduction. This project will involve the use of analytical detection systems, cell culture techniques and in vitro bioassay development.

For further information contact: Dr Bart Van der Burg (Bart.van.der.Burg@bds.nl)

APPLY

by sending a CV and letter of motivation to Dr Bart Van der Burg (Bart.van.der.Burg@bds.nl)