Elizabeth Goya Jorge obtained her Master´s degree in Pharmaceutical Sciences from the Universidad Central “Marta Abreu” de las Villas (Cuba) in 2016. A year earlier, she graduated with honors as a Bachelor in Pharmacy from the same institution, where she was also training as a graduate teaching assistant and a junior researcher during two years.
Science-related Work Experience:
Elizabeth carried out the research that led to her Bachelor´s and Master´s theses in the field of the antioxidant activity, especially focused on the free radical scavenging capacity of compounds commonly found as secondary metabolites of plants. In this sense, she conducted in silico and in vitro determinations, creating computational tools experimentally validated to predict the antiradical activity of compounds, using DPPH assay results of thousands of chemical structures with a wide diversity. An artificial neural network was developed with predictive purposes, and it was published in the International Journal of Molecular Sciences by Elizabeth (first author) and her co-workers in 2016. She worked on a collaborative project with the Equipe de Chimie Moléculaire from the Conservatoire National des Arts et Métiers (CNAM, Paris). This study consisted of exploring the obtaining process and the antioxidant activity of synthetic compounds as benzalacetones and coumarin derivatives. Results from this project were published as two Proceeding Papers of the International Conference MOL2NET. During November to December of 2016 she attended to a practical lab training in analytical and organic chemistry at CNAM. As part of a NORTH-SOUTH-SOUTH project with the Vrije Universiteit Brussel during 2017, she worked in the topic of Chromatographic Fingerprint Analysis of plant derivative products. The aim of this project was to use a combination of analytical and chemoinformatic tools to develop, optimise and validate natural products, especially potential herbal medicines. Elizabeth has now been admitted at the Doctoral School of the Universitat de València to develop her PhD in the Chemistry Program. She works as a research fellow in ProtoQSAR SL, with the purpose of in silico modeling the endocrine disrupting activity of compounds and mixtures under the MSCA_ITN “PROTECTED” project grants.
Other Professional Points-of-Interest:
Elizabeth has a great interest in the theoretical elucidation of the mechanisms of action of endocrine disrupting compounds. She is a licensed pharmacist and was trained as university teaching assistant in the field of pharmacology and pharmacotherapy. She speaks Spanish as her mother tongue and is able to use English for scientific purposes.
Area of science:
Rafael is a computational chemist with expertise in the application of in silico approaches to drug discovery, and in particular the development of QSAR multivariate models (for physico-chemical, ADME-T and biological predictions), docking and study of protein-ligand interactions, design of virtual target-focused and diverse chemical libraries, pharmacophore hypotheses generation and virtual screening for selection of hit candidates.
Rafael holds a PhD in Physical Chemistry from the University of Valencia, Spain (1998). After a post-doctoral position at the “Groupe de Chimie Informatique et Modélisation” (ITODYS - CNRS) and Faculté de Médecine, both at the Université Paris VII, he spent seven years as senior scientist at the Modelling group of CEREP, a French biotech company. In 2007 he moved to the Structural Biochemistry Laboratory of the Centro de Investigacion Principe Felipe (CIPF) in Spain, where he had the responsibility of the chemoinformatics and molecular modelling activities of the group. In 2012, he founded the company ProtoQSAR SL, and he is currently the Director.
Supervisor of ESR 11 (QSAR modelling endocrine disruptors and their mixtures).
Area of science:
Merete Eggesbø is an environmental epidemiologist with expertise in adverse effects of environmental chemicals and gut microbiota. Merete leads a small research group in environmental epidemiology, secured by her own grants. Having obtained an MD from the University of Oslo and a PhD in epidemiology and food allergy Merete is the Principal Investigator of the prospective HUMIS & NoMIC birth cohorts, which was established in order to study environmental toxicants and gut microbiota and child health. The cohorts encompass more than 2600 children and an extensive longitudinal data collection. Publications to date include the role of persistent toxicants such as HCB, PCB, DDE, BFRs and PFCs, as well as the composition of gut microbiota, in early life for child health.
Merete is affiliated with the Dept. of Environmental Exposure and Epidemiology Norwegian Institute of Public Health and has an extensive network of international collaborators. Merete is also an appointed consultant on a contract with NIEHS, NC, US, on research on environmental samples in MoBa.
Supervisor of ESR 2 (Identifying mixtures of contaminants associated with adverse child health outcomes)